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1、JournalofAntimicrobialChemotherapy(2008)62,534doi:10.1093/jac/dkn162AdvanceAccesspublication29April2008Guidelinesforthemanagementofhospital-acquiredpneumoniaintheUK:ReportoftheWorkingPartyonHospital-AcquiredPneumoniaoftheBritishSocietyforAntimicrobialChemotherapyR.G.Masterton1*,A.Galloway2,G.Frenc

2、h3,M.Street4,J.Armstrong5,E.Brown6,J.Cleverley7,P.Dilworth8,C.Fry9,A.D.Gascoigne10,AlanKnox11,DilipNathwani12,RobertSpencer13andMarkWilcox1412DepartmentofMicrobiology,CrosshouseHospital,Kilmarnock,UK;DepartmentofMicrobiology,Royal3VictoriaInfirmary,QueenVictoriaRoad,Newcastle-upon-Tyne,UK;Departmen

3、tofInfection,Guy’sand4StThomas’sNHSFoundationTrustandKing’sCollege,StThomas’Hospital,London,UK;Departmentof5IntensiveCare,RoyalSussexCountyHospital,Brighton,UK;DepartmentofPublicHealth,NorthDurham6StrategicHealthAuthority,EarlsHouse,Durham,UK;DepartmentofMicrobiology,FrenchayHospital,78Downloadedf

4、romBristol,UK;DepartmentofRadiology,RoyalFreeHospital,London,UK;DepartmentofThoracicMedicine,910RoyalFreeHospital,London,UK;DepartmentofHealth,London,UK;RoyalVictoriaInfirmary,Queen11VictoriaRoad,Newcastle-upon-Tyne,UK;RespiratoryMedicineUnit,CityHospital,Nottingham,UK;1213jac.oxfordjournals.orgInf

5、ectionUnit,NinewellsHospitalandMedicalSchool,Dundee,UK;HealthProtectionAgency,14BristolRoyalInfirmary,MarlboroughSt,Bristol,UK;UniversityofLeeds,Leeds,UKTheseevidence-basedguidelineshavebeenproducedafterasystematicliteraturereviewofarangebyguestonOctober15,2011ofissuesinvolvingprevention,diagnosisa

6、ndtreatmentofhospital-acquiredpneumonia(HAP).Preventionisstructuredintosectionsaddressinggeneralissues,equipment,patientproceduresandtheenvironment,whereasintreatment,thestructureaddressestheuseofantimicrobialsinpreventionandtreatment,adjunctivetherapiesandtheapplicationofclinicalprotocols.Thesect

7、ionsdealingwithdiagnosisarepresentedagainsttheclinical,radiologicalandmicrobiologicaldiagnosisofHAP.Recommendationsarealsomadeupontheroleofinvasivesamplingandquantitativemicrobiologyofrespiratorysecretionsindirec