发热止痛贴治疗膝关节骨性关节炎的临床研究

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1、黑龙江中医药大学硕士学位论文发热止痛贴治疗膝关节骨性关节炎的临床研究姓名：李建有申请学位级别：硕士专业：中西医结合临床指导教师：董清平2003.5.1缩赌港表菱文0A英文全稼MMPsMatrixmetallo_proteinase羊i菊lpgTissueinhibitorsofmetaltoproteinasep毯S擎ILSODN嵇下封S善f鼙中文全称嚣性关繁炎基壤金溪蛋熬瓣螽淄骚瘩酶猕涮物prostaglandin饕剃艨囊Psubstancetransdermdeliverysystemtransdermthe

2、rapeuticsy‘stem≯翱簇鑫潮慈赍素超载证黪装裁酶一裁耗氮经旋给努系统经戏渣疼系缆臻篓f豢美攀露靛美苇炎是～饕鬻懿魏疆蔡美繁麟露攒譬凳皇，襄燮鬃及软骨下嚣、滑膜嗣关节周豳缎织为褥饺的一静慢性膝关节痰瘸。冀瘸戮瘸囊仍泰鹤确，现瓣段，隧饕人

3、暖老龄化豳蘸舶重，藤关节嚣瞧芙节爨熬发瘸攀瞧嚣淤上舞，两零瘸程羚疗方瑟舔滏寒黻褥突袋装避震。蓥涛平教授糨摅多年戆藤经骏，黪雅台畿鼗中鼹蓊理及瀵藏啜牧避谂鼷成了辩疗膝关节糟性关节炎熟魏中药努滋漤裁一一发热壹痰憋，褒爨慕节餐整关节鼗戆中驳蓑渣疼方蘧尝试了一条耨的途凝。乒本璎

4、姘究瓣66镄瓣关节曹缝关繁炎戆畿袋黧醚枫尉照酶方法遴褥麟察，撩慕震统计擎方法缝瑾，娲床躐察结巢袭嚼，两缝惑疗效黧辏《p孀．05)，霄嚣薯建麓露；症状疗效嚣缀游愆较，试验艇巍溥除黪瓣，魏蛰装繁秘辘、西常生活晌麓力鞠黻大步行躐离骞瑟毯予潜蘸爨《P<0。05》，眷照著媛差黪；奁美节瓣藤穷蘸鞘鼹壤予对蘸缝(P<0。0t)，骞蒜赘盛蔫牲整髯；嚣缎瓣骜貔也瘸起效时间波罐持时麟(p》0．05)，蕊组阕嚣稿燕差粼。遴避缎外热像圈蕊察：发热止痛贻熊够敬善微循环障碍，掇漪鼹鄱趣溅萋。本实验谎鹈；发热正瘫辩对艨关节曹饿美苇裘畜怒簿滚疗

5、襻爨，显疗效爨予翥星虎瓣帮。关键谯；艨美节餐缎餐蕊美繁蹩；发热止瘸贼j聩零鼹敦轰嚣ST装赢e下Osteoarthritis(OA)iSacommondiseasewhichalwaysdestroysarticularcartilageanddamagesbonebeneathcartilage、synoviumandtissuesaroundjoint．It’spathogenesishasbeenuncertain。Asagingsocietycoming，incidencerateofOAhasgradua

6、llyincreased．HowevertreatmentsofOAhaven’tdeveloped．Baseonclinicalexperience,ProfessorDongqingpingcombinedmodernChineseherbmedicinepharrnaistwiththeoryofTDSandmamufacturedFRZTTI登whichisapureChineseherbpreparationthatexternaluse。Inordertoobservethecliniealeffec

7、tsofFRZTTIEforOAofknee，66casesof0AofkneeweredividedintotheexperimentalgrouptreatedbyFRZT髓EandthecontrolgrouptreatedbyNXZ芝GA◇atrandom．Theresultshowedth敷therewasasignificantlydifferenceincomparingthetotaleffectiveratesofthetwogroups(P《O。05)．Therewassignificantd

8、ifferenceinrelievingache，improvingdysfunctionofjoint，improvingthecapacityofdairyliveandwalking(P<0．05)，therewasobviouslysignificantdifferenceinswellingofjointfP<舀．01)+therewasnodifferenceintimethattakeeffeetandduration。ObservedthoughthermalinfraredimageFRZTTI

9、EcouldimprovemierocirulationandraisepartbloodflowItwassuggestedthatFRZTTIEandNXZTGAOhadsignificanteffecttooAofknee。howeverFRZTTIEiSsuperiortoNXZTGAOinsomeaspectsKeywords：OsteoarthritisFRZ