浅层脂肪抽吸术后皮肤质量的改变

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1、万方数据中国美容医学2005年12月第14卷第6期ChineseJournalofAestheticMedicine．Dec．2005．V01．14．No．6679·整形美容·浅层脂肪抽吸术后皮肤质量的改变朱桂英，，宫昔愿z(1．山东大学第二医院美容整形烧伤中心山东省济南市250033；2．济南市中心医院整形科)·论著·[摘要]目的：探讨浅层脂肪抽吸术对抽吸区皮肤质量的影响。方法：对4头家猪进行浅层脂肪抽吸手术，分别于术后2周、4周、2个月、4个月收集术区以及对照侧全层皮肤标本，进行组织形态学观察，包括皮下脂肪厚度变化、组织学变化、真皮内的成纤维细胞的数量变化、

2、真皮及皮下组织中的纤维变化进行了对照研究。结果：大体标本显示抽吸区皮下脂肪厚度降低，抽吸区的皮肤收缩；HE染色显示手术区与对照组脂肪细胞形态无改变，成纤维细胞数量增加，脂肪组织结构于术后4个月恢复正常；胶原VG染色显示术区胶原沉积且排列紊乱，网状纤维及弹力纤维于术后2个月显著增生，于4个月时基本恢复正常。结论：浅层脂肪抽吸术通过破坏真皮下脂肪，损伤、刺激真皮收缩而引起皮肤显著收缩；浅层脂肪抽吸术后皮下脂肪内抽吸隧道形成新的纤维网，皮肤重建在真皮层产生新的胶原，使皮肤收缩。[关键词]浅层脂肪抽吸术；胶原纤维；成纤维细胞；皮肤收缩[中图分类号]R622[文献标识码】

3、A[文章编号]1008—6455(2005)06-0679-02ThebasicstudyofsuperficialsubdermalliposuctioninthequalitychangeoftheoverlyingskinZHUGui—ying，GONGXi—yuan(DepartmentofBurnsandPlasticSurgery，1．TheSecondHospitalofShandongUniversity，2．DepartmentofPlasticSurgery，Jinancentralhospital，Jinan250033，ShandongP

4、rovince，China)Abstract：ObjectiveToinvestigatethepathologyoftheoverlyingskininthetreatedareaaftersuperficialsubdermalliposuctiononanimals．MethodsSuperficialsubdermalliposuctionwereoperatedonfourpigs(3femalepigsand1malepig)．Tissuesamplesofwholelayerskinwereharvestedfromtheoverlyingskin

5、on2,4．8and16post-operationweeksforhistomorphologyexaminationincludingmacroscopicalobservationandhistologicalstudyandthequantityOffibroblastandfibro—changeindermal．ResultsMacroscopicalobservationshowedthethicknessofthesubcutaneOuSadiposeofthetreatedsitejsthinnerthanthecontrolledsites．

6、Theskinoverlyingthetreatedareacontracted．Histologicalstudy(HE)showednosignificantdifferenceinadipocytemorphologybeMeenthetwokindofsamples．TheamountsofthefibroblastinthedermaIincreased．Thestructureoffattissuerecoverednormallyduring4monthsafterSSL．CollagenVGstainingshowedthecollagenfib

7、ersdepositedandirregular．Theelasticandreticularfibersproliferatedsignificantlyon2monthsaftertreatmentandrestoredtonormaon4monthsafterSSL．ConcIusionThesignificantcontractionoftheskinjssecondarytodermaIcontracturecausedbysurgical”trauma”inflictedontheundersurfaceofthedermis．Inadditions

8、uperficialsu