润燥明目汤治疗干眼病的临床研究

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1、屮文摘要目的：木课题以随机对照的临床实验方法，研究润燥明目汤对干眼病的临床疗效，寻求屮医药治疗干眼病的冇效途径。方法：本课题以符合入选标准的干眼病患者为研究对象，采用随机对照实验设计方法将60例病人分为两组。实验组30例，60只眼，采用润燥明目汤内服配合局部熏蒸法治疗，对照组30例，60只眼，单纯采用泪然滴眼液治疗；以上两组均治疗一个月为一疗程。以临床症状、泪液分泌量、泪膜破裂时间及角膜荧光索染色为疗效指标，观察患者治疗前后诸指标的变化情况。结果：治疗后，实验组症状疗效方面总有效率为86.66%,对照组为70.0

2、0%,治疗前与治疗后比较两组均有显著性差异，症状积分两组组间比较有显著性差异，提示在改善临床症状方面实验组疗效优于对照组；在泪液基础分泌测试中，实验组治疗前与治疗后比较有显著性差界,对照组治疗前与治疗后比较无显著性差异，提示实验组在增加泪液分泌量方面疗效优于对照组；在泪膜破裂时间测试屮，治疗前与治疗后比较两组均有显著性差异，治疗后两组组间比较亦有显著性差异，提示实验组在延长泪膜破裂吋间上优于对照组；在角膜荧光素染色积分测试中，治疗前与治疗后比较两组均有显著性差异，治疗后两组组间比较无显著性差异，提示两组疗效相当。

3、结论：润燥明目汤治疗干眼病，不仅改善了干眼病患者的临床症状，同吋也增加了泪液分泌量，延长了泪膜破裂吋间，减少了角膜荧光素染色点数，同吋，润燥明目汤安全，无肝肾功损害等不良反应。主题词：干眼病；润燥明口汤;泪然滴眼液;临床研究ABSTRACTObjective:ToobservetheclinicalcurativeeffectofSmoothdry&CleareyesSoupforeye-drieddiseasewithclinicalcontrolexperiment^designmeansrandomly.T

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