[精品]住院早产儿医院感染临床分析

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1、住院早产儿医院感染临床分析住院早产儿医院感染临床分析【摘要】目的探讨早产儿医院感染发生率(院感率)的相关高危因素，揭示其病原学特点，指导临床工作。方法对869例早产儿的临床相关资料进行调查、登记和分析，总结早产儿医院感染(院感)与岀生体重、住院天数的关系，分析其病原体和耐药情况。结果869例早产儿院感率为3.6%,其中101例极低出生体重(VLBW)儿院感率10.9%,768例低出生体重(LBW)儿院感率2.6%❷；足月儿院感率仅0.7%；早产儿院感多发生在住院的第2〜3周，VLBW儿院感多发生在第3周，LBW儿院感多发生在

2、第2周；早产儿院感以下呼吸道感染最多见，其次为皮肤黏膜感染;病原体大多数是革兰氏阴性(G-)杆菌，其中肺炎克雷伯杆菌肺炎亚种高达57.1%,产ESBL酶杆菌和MRSA葡萄球菌达80.0%o结论早产儿尤其VLBW儿易发生院感，住院后2~3周内出现呼吸道感染多见，病原菌以耐药G-杆菌(肺炎克雷伯杆菌肺炎亚种)为主，临床上应高度注意，防止其在新生儿病室暴发传播。【关键词】医院感染；早产儿；病原学；耐药性AClinicalAnalysisofHospitalizedPrematureNeonates，NosocomialInfect

3、ionFANYan-zhou,XIAOZhengxiang.(DepartmentofPediatrics,ZhuzhouPeople'sHospitalDepartmentofPediatrics,ZhuzhouAffiliatedHospital,ChangshaMedicalCollege,Zhuzhou,412000,China)[Abstract]ObjectivesToprobethefactorsthatcausetheinfectionofthehospitalizedprematureneonatesand

4、revealthefeaturesofitsetiologicalfeaturesandthereforeprovideaguidelinefortheclinicalpractice・MethodsByinvestigating,andscreeningthedocumentsof869hospitalizedprematureneonates,thepapertriestoestablishandidentifytherelationshipbetweentherateoftheirinfectionandtheirwe

5、ightatbirthandthedaysinhospital,andmakeasystematicanalysisoftheirspecificpathogensanddrugtolerance・ResultsTheresearchrevealsthat3.6%ofthe869prematureneonatesdevelopedhospitalinfection.10.9%of101prematureneonateswithverylowbirthweight(VLBW)developedinfection,and2.6%

6、of768prematureneonateswithlowbirthweight(LBW)developedinfection,whiletherateofhospitalizedmatureneonatesisonly0.7%.Mostcasesofhospitalinfectionoccurredinthesecondorthirdweek・PrematureneonateswithVLBWwereofteninfectedintheirthirdweek・,andprematureneonateswithLBWinth

7、eirsecondweek・Thehospitalinfectionofprematureneonateswascharacterizedbytheinfectionoflowrespiratorytractandsecondskinormembrane・MostoftheinfectiouspathogensarethesubspeciesofGram-negativebacillus,ofwhichthesubspeciesofKlebsiellapneumoniaeaccountedfor57.1%,andESBLba

8、cillusandMRSAstaphylococci80.0%.ConclusionPrematureneonates,especiallythosewithVLBW,arepredisposedtonosocomialinfection,whichoftenoccursintheirse