冠状病毒Coronavirusl论文-2014 The Hajj pilgrimage and surveillance for Middle East Respiratory syndrome coronavirus in pilgrims from African coun.pdf

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1、TropicalMedicineandInternationalHealthdoi:10.1111/tmi.12318volume19no7pp838–840july2014EditorialTheHajjpilgrimageandsurveillanceforMiddleEastRespiratorysyndromecoronavirusinpilgrimsfromAfricancountries1,2,3,422,31,56AlimuddinZumla,PeterMwaba,MatthewBates,JaffarA.Al-Tawfiq,Marku

2、sMaeurerand1ZiadA.Memish1GlobalCentreforMassGatheringsMedicine,MinistryofHealth,Riyadh,SaudiArabia2UNZA-UCLMSResearchandTrainingProgramme,UniversityTeachingHospital,Lusaka,Zambia3DivisionofInfectionandImmunity,UniversityCollegeLondon,London,UK4UCLHospitalsNHSFoundationTrust,Lo

3、ndon,UK5SaudiAramcoMedicalServicesOrganization,SaudiAramco,Dhahran,SaudiArabia6TherapeuticImmunologyDivision,DepartmentofLaboratoryMedicine,KarolinskaInstitutet,Stockholm,SwedenkeywordsMERS-CoV,Respiratorytractinfections,Africa,Hajj,Screening,camels,coronavirusItiswelldocument

4、edthatmassgatheringsattractingpeo-infectiousdiseases,someofwhichmayhaveepidemicplefromallovertheworldcreateanidealenvironmentpotential(AlRabeeahetal.2012;Al-Tawfiq&Memishforrapidtransmissionandspreadofviralandbacterial2012).Forexample,RiftValleyfeverfromEastAfricarespiratoryinf

5、ections(Abubakaretal.2012).AfricahascausedoutbreaksinKSAandYemen(Fagbo2002),andalargeMuslimpopulationestimatedatover250milliontherehavebeentwoimportantmeningococcaldisease(Government2011).Everyyear,morethan1millionpil-outbreaksinKSArelatedtotheHajj(al-Gahtanietal.grimsfromAfri

6、cancountriestraveltoMakkahand1995;Aguileraetal.2002).Madinah,KingdomofSaudiArabia(KSA)tojoin10Thepast15yearshaveseentheemergenceofseveralmillionotherpilgrimsfromaroundtheglobetoperformkillerrespiratorytractinfectiousdiseaseswithepidemiceithertheannualHajjpilgrimage(Figure1)ort

7、heUm-potentialthatgeneratedglobalhealthalertsfromWHO.rah,whichcanbeperformedatanytimeoftheyearNotablethreatshavecomefromavianinfluenzaviruses,(Memishetal.2014a).OneofthemajorpublichealththeSevereAcuteRespiratorySyndromeCoronavirusconcernsrelatedtothesejourneysistheimportationon

8、(SARS-CoV)and,morerecently,theMiddleEastRespira-arrival,orexp