素注射治疗婴儿血管瘤临床对比研究魏.doc

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1、A群链球菌制剂、平阳霉素联合强的松龙注射治疗体表血管瘤和脉管畸形的临床对照研究魏海刚'邱雅'陈玉婷'李蜀光'1广东省佛山市第二人民医院口腔颌面外科528000【摘要】目的前瞻性观察并评价A群链球菌制剂和平阳霉索注射治疗颌面部血管瘤、静脉畸形和淋巴管畸形的治疗效果。方法选取门诊及住院颌而部脉管瘤120例，随机分组采用A族链球菌制剂和平阳霉素注射治疗，对所有病例进行随访,并记录其疗效及毒副作用。结果血管瘤36例,A群链球菌制剂组15例，治愈8例(53.33%);平阳每素组21例，治愈12例(57.14%)o静脉畸形40例,A族链球菌制剂治疗组19例，治愈13例(6&42

2、%);平阳霉索组21例，治愈14例(66.67%)o淋巴管畸形44例,A族链球菌制剂治疗21例，治愈14例(66.67%);平阳霉素治疗23例，治愈6例(26.09%)。结论A族链球菌制剂注射治疗淋巴管畸形效果更为明显，八族链球菌制剂和平阳每素注射治疗血管瘤和静脉畸形均有效。【关键词】血管瘤；静脉畸形；淋巴管畸形；A族链球菌制剂；平阳霉素作者简介：魏海刚男37岁医学硕士副主任医师课题负责人通讯作者：李蜀光男47岁医学博士主任医师研究方向；口腔颌而整形(基金项目：佛山市科技局医学专项基金立项，立项编号：200908080)ComparisonbetweenStrept

3、ococcusAgrouppreparationforinjectionandpingyangmycinintreatmentofbodysurfacehemangiomasandvascularmalformationWeihaigang1Qiuya1Chenyuting1Lishuguang11FoshanSecondPeople"sHospital,Guangdong528000【Abstract]ObjectiveToevaluateandcomparetheefficacyofStreptococcusAgrouppreparationforinjecti

4、onandpingyangmycinintreatmentofbodysurfacehemangiomas,venousmalformationandlymphaticmalformation.Methods120patientswithbodysurfacevasculartumorswererandomlydividedintotwogroups,onegroupwasgivenstreptococcusAgrouppreparationforinjection,andtheothergroupwasgivenpingyangmycin.Thetherapeut

5、icefficacywasrecordedandthepatientswerefollowedupforonetofiveyears・ResultsIn36hemangiomapatients,theeffectiverateofstreptococcusAgrouppreparationforinjectionwas53.33%,theeffectiverateofpingyangmycinwas57.14%.In40venousmalfonnationpatients,theeffectiverateofstreptococcusAgrouppreparatio

6、nforinjectionwas68.42%、andtheeffectiverateofpingyangmycinwas66.67%・In44lymphaticmalformationcases,theeffectiverateofstreptococcusAgrouppreparationforinjectionwas66.67%whichwasobviouslyhigherthantheeffectiverateofpingyangmycin26.09%.ConclusionTheefficacyofStreptococcusAgrouppreparationf

7、orinjectionintreatmentoflymphaticmalformationisbetterthanpingyangmycin.TreatmentwitheitherStreptococcusAgrouppreparationforinjectionorpingyangmycininhemangiomasandvenousmalformationiseffective.【Keywords]Hemangiomas；Venousmalformation;Lymphaticmalformation;StreptococcusAgrouppreparati