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1、功能性消化不良伴焦虑Hp感染者根除Hp治疗疗效观察【摘要】目的:对幽门螺杆菌(helicobacterpylori,Hp)感染功能性消化不良(functionaldyspepsia,FD)伴焦虑者根除Hp治疗，研究根除Up治疗的必要性。方法：选择85例FD伴焦虑症状Hp感染患者,分为治疗组42例和对照组43例，治疗组在常规治疗的的基础上进行根除Hp治疗，对照组采用常规治疗。比较两组患者治疗结束后6个月、12个月的ZUNG焦虑自评量表评分和疗效。结果：治疗6个月后，治疗组总有效率为64%,对照组为40%,两组比较
2、差异有统计学意义(P〈0・05)；治疗12个月后，治疗组总有效率为69%,对照组为43%,两组比较差异有统计学意义(1X0.05)。治疗后6个月和12个月，ZUNG焦虑自评量表评分两组比较差异均有统计学意义(P<0.01)o结论：FD伴焦虑症状的Hp感染者在常规治疗的基础上根除Hp治疗，对改善FD伴焦虑症状疗效优于常规治疗,Hp感染存在诱发或加重焦虑症状的倾向，应进行根除Hp治疗。【关键词】功能性消化不良；焦虑；幽门螺杆菌TheCurativeEffectObservationofHpEradicationTh
3、erapyfortheAnxietyFD卩atientswithHPTnfection/XTEKun-hua,TANGShang-wei,YANGZhi-zhai,etal.//MedicalInnovationofChina,2014,11(01)：001-003[Abstract】Objective：TostudythenecessitiesofHperadicatetherapyinanxietyFDpatientswithUpinfection.Method：85FDwithanxietyHpinfec
4、tedpatientsweredividedinto2groups:thetreatment,groupandthecontrolgroup.Thetreatmentgroupwith42caseswereaccepttheHperadicatetherapyonthebasisofconventionaltreatment,whilethecontrolgroupwith43caseswerejustaccepttheconvenlionaltreatment•Theindicatorsbetweenthet
5、wogroupswerecomparedaftertreatment6monthsand12months,suchastheeffectiverate,theself-ratinganxietyscaleofZUNGpoint.ResuIt：Thetotaieffectiverateofthetreatnientgroupfor6monthswas64%,for12monthswas69%,whilethetotaleffectiverateofthecontrolgroupfor6monthswas37%,f
6、or12monthswas43%,andthedifferencebetweenthetwogroupswereallstatisticallysignificant(P<0.05)・TheZUNGselfratinganxietyscalescoreofthetreatmentgroupfor6monthsand12monthsweresignificantlowerthanthecontrolgroup(P<0.01)・Conclusion：FDwithanxietypatientswhoacceptthe
7、Uperadicatedtherapyonthebasisofconventionaltreatmenthaveabettercurativeeffectthanonlyacceptconventionaltreatment.TheinfectionoftheHpmayinduceorexacerbatetheanxietytendencyoftheFDpatients.PatientsinfectedwithFDandanxietyHpshouldaccepttheHperadicationtherapy.[
8、Keywords】Functionaldyspepsia；Anxiety；HelicobacterpyloriFirst-author*saddress：ThePeople'sHospitalofFangchengDistrictofFangchenggangCity,Fangchenggang538021,Chinadoi：10.3969/j.issn.1674-4985.2014.
