丹参联合阿托伐他汀钙对急性脑梗死患者血清C-反应蛋白水平和血脂的影响-论文.pdf

《丹参联合阿托伐他汀钙对急性脑梗死患者血清C-反应蛋白水平和血脂的影响-论文.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、TEAT工目E论著ieH工NAEAL7-H工N口UBT口Y丹参联合阿托伐他汀钙对急性脑梗死患者血清c一反应蛋白水平和血脂的影响郭宇辽宁省精神卫生中心神经内科．辽宁开原112300[摘要】目的探索丹参联合阿托伐他汀钙对急性脑梗死患者血清c一反应蛋白水平和血脂及脑梗死复发的影响。方法选择急性脑梗死患者80例随机均分为对照组(n=40)和观察组(n=40)。对照组为常规治疗，观察组为在常规丹参治疗的基础上加用阿托伐他汀，观察t4d后临床疗效及治疗前后两组血清C一反应蛋白及血脂的变化。结果观察组总有效率为87．5％，

2、对照组总有效率为70％，两组比较，差异显著(P=0．034<0．05，x=4．41)。观察组CRP水平由治疗前(14．94~5．75)降至(6．89~4．12)，差异显著(P<0．01)；而对照组CRP水平治疗前后略有下降，差异无显著性意义。血脂各指标中观察组治疗后均明显下降，差异有显著性(PO．05)。结论观察组患者血清CRP水平明显低于对照组，血脂指标均明显下降，降低了脑梗死的复发。因此，对急性脑梗死患者治疗采用丹参联合阿托伐他汀钙效果明显优于

3、丹参单独治疗。【关键词】阿托伐他汀；c一反应蛋白；急性脑梗死【中图分类号】R743【文献标识码】A【文章编号】1672—5654(2014)06(b)一0017—02EfectofDanshencombinedwithatorvastatinonbloodlipidandC-reactiveproteininpatientswithacutemyocardialinfarctionGUOYuMentalHealthCenterofLiaoningProvince，Kaiyuan112300，China【Abs

4、tract】ObjectiveToexploretheeffectsofstatinsatorvastatinandcalciuminpatientswithacutecerebralinfarctionserumlevelsofC—reactiveproteinandlipidrecurrenceofcerebralinfarction．Methods80casesofpatientswererandomized：controlgroup(n=40)and(n=40)．Conventionaltreatme

5、ntcontrolgroup，theobservationgrouponthebasisofconventionaltherapyplusa—torvastatinandDanshen，theclinicaleficacyoftwo14-dayjudgment．ObservedbeforeandaftertreatmentlevelsofserumC—re—activeproteinandlipid．ResultsTotaleffectiveratewas87．5％inthecontrolgroup．thet

6、otaleffectiveratewas70％inbothgroups，thedifferencewassignificant(尸=0．034<0．05，X2=4．41)．CRPlevelswasobservedbythegroupbeforetreatment14．94+5．75decreasedto6．89~4．12(P<0．01)，eachindexlipidswereobservedinthetreatmentgroupwassignificantlydecreased<0．05)；whilethec

7、ontrolgroupbeforeandaftertreatmentCRPlevelsandeachindexlipidsweredecreased，butnotstatisticallysignificant(P>O．05)．ConclusionCRPlevelsinpatientsintheobservationgroupwassignificantlylowerthanthecontrolgroup，serumlipidsweresignificantlydecreased，reducingtherec

8、urrenceofcerebralinfarction．Therefore，inpatientswithacuteeerebrMinfarctionusingDanshenandatorvastatinisbetterthanDanshenmonotherapy．[Keywords】Atorvastatin；C-reactiveprotein；Acutecerebralinfarction脑梗死又称