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时间:2020-05-02
《Narcotrend麻醉深度监测在小儿全身静脉麻醉中的应用.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中华妇幼临床医学杂志(电子版)2014年8月第1O卷第4期·93·论著·Narcotrend麻醉深度监测在小儿全身静脉麻醉中的应用黄俊祥宋兴荣田航李碧莲倪锦【摘要】目的探讨Narcotrend麻醉深度监测在小儿全身静脉麻醉中的临床效果。方法选择2Ol3年6月~1i月于广州市妇女儿童医疗中心住院治疗的4O例择期腹部手术患儿为研究对象,按照人院序号,将其随机分为研究组(n:20)和对照组(一20)。本研究遵循的程序符合广州市妇女儿童医疗中心人体试验委员会所制定的伦理学标准,得到该委员会批准,分组征得受试对象监护人的知情同意,并与之签署临床研究知情同意书。两组患儿均接受
2、丙泊酚一瑞芬太尼全身静脉麻醉,研究组患儿术中接受Narcotrend麻醉深度监测,对照组患儿术中根据常规l临床监测指标调节麻醉深度。监测两组患儿术前、麻醉诱导后、手术开始、手术结束、拔管5个时间点的心率(HR)、平均动脉压(MAP)。记录苏醒时间及拔管时间、丙泊酚和瑞芬太尼的用量及术后不良反应发生率。结果两组患儿5个时间点HR和MAP的变化分别比较,差异均无统计学意义(P>0.05),而研究组息儿全身麻醉中丙泊酚用量、术后苏醒时间及拔管时间均显著小于对照组[(122.714_-21.06)mg"o5.(181.08±25.97)mg,(4.37±2.05)min7
3、7s.(9.15±5.13)min,(6.68±2.32)min"us.(12.45±5.15)mini,并且差异有统计学意义(P4、sthesiainChildrenHuangJunxiang,SongXingrong,TianHang,LiBilian,NiJin.DepartmentofAnesthesiology。GuangzhouWomenandChildrenMedicalCenter,Guangzhou510120,GuangdongProvim’,China.(Correspondingauthor:SongXingrong,Email:songxrl966@aohu.corn)[Abstract]ObjectiveToexploretheapplicationofNarcotr5、end—assistedanesthesiain-depthmonitorduringtotaIintravenousanesthesiainchildren.MethodsFromJunetoNovember2O13,atotalof4Ochildrenwhounderwentabdominalsurgerywereincludedinthestudyrandomly.TheyweredividedintoNarcotrendgroup(一20)andcontrolgroup(:20).Allpatientsreceivedtotalintravenousane6、sthesiawithpropofolandremifentanil.ThepatientsinNarcotrendgroupadjustedanesthesiain—depthaccordingtoNarcotrendindex(NTI).Thosepatientsincontrolgroupadjustedanesthesiain—depthaccordingtotheirheartrate(HR),meanarterialpressure(MAP)andmovement.Changesofhemodynamics,durationsofemergencean7、dtrachealextubationwererecorded.Thedosesofpropofolandremifentanilandtheincidenceratesofpostoperativenaseaandvomitingwerealsorecorded.ThestudyprotocolwasapprovedbytheEthicalReviewBoardofInvestigationinHumanBeingofGuangzhouWomenandChildrensMedicalCenter.Informedconsentwasobtainedfromeac8、hpart
4、sthesiainChildrenHuangJunxiang,SongXingrong,TianHang,LiBilian,NiJin.DepartmentofAnesthesiology。GuangzhouWomenandChildrenMedicalCenter,Guangzhou510120,GuangdongProvim’,China.(Correspondingauthor:SongXingrong,Email:songxrl966@aohu.corn)[Abstract]ObjectiveToexploretheapplicationofNarcotr
5、end—assistedanesthesiain-depthmonitorduringtotaIintravenousanesthesiainchildren.MethodsFromJunetoNovember2O13,atotalof4Ochildrenwhounderwentabdominalsurgerywereincludedinthestudyrandomly.TheyweredividedintoNarcotrendgroup(一20)andcontrolgroup(:20).Allpatientsreceivedtotalintravenousane
6、sthesiawithpropofolandremifentanil.ThepatientsinNarcotrendgroupadjustedanesthesiain—depthaccordingtoNarcotrendindex(NTI).Thosepatientsincontrolgroupadjustedanesthesiain—depthaccordingtotheirheartrate(HR),meanarterialpressure(MAP)andmovement.Changesofhemodynamics,durationsofemergencean
7、dtrachealextubationwererecorded.Thedosesofpropofolandremifentanilandtheincidenceratesofpostoperativenaseaandvomitingwerealsorecorded.ThestudyprotocolwasapprovedbytheEthicalReviewBoardofInvestigationinHumanBeingofGuangzhouWomenandChildrensMedicalCenter.Informedconsentwasobtainedfromeac
8、hpart
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