早发型子痫前期孕妇保守治疗后出现不良妊娠结局研究

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1、早发型子痫前期孕妇保守治疗后出现不良妊娠结局研究连文艳陈倩初晓丽郭海香沈润华杨建敏(广州医科大学附属深圳沙井医院产科518104)【摘要】目的分析早发型子痫前期孕妇保守治疗后产生的不良妊娠结局。方法170例早发型子痫前期孕妇以孕周34周为界限，分为早发型重度子痫前期组(早发组＞84例和晚发型重度子痫前期组(晚发组)86例。比较两组一般情况、并发症、围生儿结局、孕妇终止妊娠和保守治疗时间。结果早发组孕妇发病孕周、终止妊娠时间均明显早于晚发组，两组相比有显著差异(P<0.05)。保守治疗时间比较两组无显著差异(P>0.05)。早发组共71例(84.5%

2、)出现并发症，晚发组共60例(69.8%)山现并发症，两组相比有显著差异(P<0.05)。早发组胎儿生长受限、胎儿窘迫、围生儿死亡、胎死宫内和新生儿死亡的发生率均明显高于晚发组，两组相比有显著差异(P均<0.05)。结论早发型重度子痫前期会产生许多严重的并发症，造成不良妊娠结局。在保证孕妇安全的同时采取保守治疗，推迟终止妊娠的时间，可以减少不良妊娠结局的发生。【关键词】早发型子痫前期保守治疗妊娠结局【中图分类号】R714【文献标识码】A【文章编号】2095-1752(2014)17-0120-02Studyofadversepregnancyout

3、comesafterconservativetreatmentinwomenwithearlyonsetpreeclampsia【Abstract】Toanalyzeadversepregnancyoutcomesafterconservativetreatmentinwomenwithearlyonsetpreeclampsia.MethodsTheclinicaldataof170patientswithearlyonsetpreeclampsiawasanalyzed.Thepatientsweredividedintotwogroupsby34gest

4、ationweeks,84patientswhohaddiseasebefore34weekswereinearlyonsetgroup,while86patientshaddiseaselaterthan34weekswereinlateonsetgroup.Thegeneralsituation,complication,perinataloutcomes,timeofpregnancyterminationandtimeofconservativetreatmentinpregnantwomenwerecomparedbetweentwogroups.R

5、esultsTheonsetofgestationalageandthetimeofpregnancyterminationinearlyonsetgroupwerebothlowerthanthatinlateonsetgroup,therehasasignificantdifferencebetweentwogroups(P<0.05).Thetimeofconservativetreatmentbetweentwogroupshasnosignificantdifference(P>0.05).Inearlyonsetgroup,therea

6、re71cases(84.5%)havecomplications,whichwerehigher(P<0.05)thanthatinlateonsetgroup(60cases,69.8%).Theincidenceoffetalgrowthrestriction,fetaldistress,theperinataldeath,fetalintrauterineandneonataldeathinearlyonsetgroupwasmorehigherthanthatinlateonsetgroup(allP<0.05).ConclusionEa

7、rlyonsetseverepreeclampsiacouldproducemanyseriouscomplicationsandleadtoadversepregnancyoutcomes.Itcandelaythetimeofterminationandreducetheoccurrenceofadversepregnancyoutcomeswhenensurethesafetyofpregnantwomenandtaketheconservativetreatmentatthesametime.【Keywords】Earlyonsetpreeclamps

8、iaConservativetreat