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1、RiskRatioforCoronaryHeartDiseaseMortalityin59RandomizedControlledTrialsofCholesterol-LoweringInterventionsStatins0.69(0.59-0.80)n=13(16,228/11,279)n-3fattyacids0.44(0.18-1.07)n=3(1,348/1,349)Fibrates0.98(0.78-1.24)n=12(9,873/11,496)Resins0.71(0.51-0.99)n=8(3,280/3,257Hormones1
2、.04(0.93-1.17)n=8(4,516/9,039)Niacinacids0.85(0.83-1.10)n=2(1,196/2,932)Diet0.91(0.82-1.01)n=16(48,481/59,042)1.0.9.8.7.6.5.4.3.2.12RiskRatio%95%CIBenefitHarmArteriosclerThrombVascBiol.1999;19:187-195RiskRatioforOverallMortalityin59RandomizedControlledTrialsofCholesterol-Lower
3、ingInterventionsStatins0.79(0.71-0.89)n=13(16,228/11,279)n-3fattyacids0.66(0.53-0.88)n=3(1,348/1,349)Fibrates1.06(0.78-1.48)n=12(9,873/11,496)Resins0.85(0.66-1.08)n=8(3,280/3,257Hormones1.09(1.00-1.20)n=8(4,516/9,039)Niacinacids0.96(0.86-1.08)n=2(1,196/2,932)Diet0.97(0.81-1.15
4、)n=16(48,441/59,042)1.0.9.8.7.6.5.42RiskRatio%95%CIBenefitHarmArteriosclerThrombVascBiol.1999;19:187-195RiskRatioforMortalityOtherThanFromCHDin59RandomizedControlledTrialsofCholesterol-LoweringInterventionsStatins0.97(0.81-1.16)n=13(16,228/11,279)n-3fattyacids1.16(0.63-2.12)n=
5、3(1,348/1,349)Fibrates1.16(0.63-2.12)n=12(9,873/11,496)Resins1.07(0.74-1.55)n=8(3,280/3,257Hormones1.29(1.08-1.57)n=8(4,516/9,039)Niacinacids0.99(0.76-1.29)n=2(1,196/2,932)Diet1.00(0.95-1.05)n=16(48,481/59,042)1.0.9.8.7.62RiskRatio%95%CIBenefitHarmArteriosclerThrombVascBiol.19
6、99;19:187-1953
