236例高热惊厥患儿的血清钠分析

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1、摘要：目的探讨高热惊厥(Fc)患儿发生血清钠降低的影响因素及其临床意义。方法对236例高热惊厥患儿血清钠浓度变化进行回顾分析。结果236病例中，女童(90/236)血钠值为(135.97±3.04)mmol/L，男童(146/236)血钠值为(134.55±3.57)mmol/L,P=0.002,女童中31.11%(28/90)有血清钠降低，男童中54.11%(79/146)有血清钠降低，x2=11.883，P=0.001；抽搐时间在30s~20min不等，分别以3min、5min及lOmin为分组界限，不同组别的患儿血清钠统计P〉0.05;既往有抽搐史者(8

2、9/236)与无抽搐史者(147/236)血钠值及血钠降低率统计学差异无显著意义；有家族史者(78/236)与无家族史(158/236)血钠值及血钠降低率统计学差异无显著意义。结论发生热性惊厥的患儿中，常存在血清钠下降，其中男性患儿发生血清钠降低比例更高；并与抽搐时间、抽搐史、家族史无明确相关。关键词：高热惊厥；血清钠；浓度236CasesofSerumSodiumLevelChangeinChildrenwithFebrileConvulsionWANGChun-hong(DepartmentofPediatrics,WuxiNo.4People’sHosp

3、ital，Wuxi214062，Jiangsu,China)Abstract：ObjectiveToinvestigateinfluentialfactorsandclinicalsignificanceofserumsodiumreductioninchildrenwithfebrileconvulsion.MethodsToanalyzeretrospectivelytheserumsodiumconcentrationchangesinchildrenwithfebrileconvulsion.ResultsIn236cases,girls(90/236

4、)serumsodiumvaluesfor(135.97±3.04)mmol/L，boys(146/236)serumsodiumvaluesfor(134.55±3.57)mmol/L,P=0.002,31.11%ofthegirls(28/90)hadlowerserumsodium，54.11%oftheboy(79/146)hadlowerserumsodium,x2=11.883，P=0.001Switchingtimerangingfrom30secondsto20minutes,3minutes,5minutesand10minutesrespe

5、ctivelygroupedboundaries,indifferentgroupsofchildrenserumsodiumstatisticsP〉0.05;serumsodiumandserumsodiumreductionratewasnosignificantstatisticaldifferencebetweenchildrenwithprevioustwitchinghistory(89/236)andnotwitchinghistory(147/236);inchildrenwithhavingfamilyhistory(78/236)andno

6、familyhistory(158/236),serumsodiumandserumsodiumreductionratewasnosignificantstatisticaldifference.ConclusionInchildrenwithfebrileconvulsion,thereisoftendecreasedserumsodium,theproportionofreductionwithserumsodiumishigherinmalechildren;andthereisnoclearcorrelationwithtwitchingtime,t

7、witchinghistory,familyhistory.Keywords：Febrileconvulsion;Serumsodium;Concentration高热惊厥是儿科常见急诊，儿童中约有5%的患儿有高热惊厥史。有报道高热惊厥的患儿往往合并有血清钠的降低。1资料与方法1.1一般资料236例高热惊厥患儿均符合高热惊厥诊断标准［1］。其中男146例，女90例，男女比1.62:1;发病年龄:在4个月〜9岁不等，平均年龄为31.1个月；抽搐时间在30s〜21min不等，平均抽搐时间3.57min,原发病：急性上呼吸道感染224例（其中化脓性扁桃体炎7例，疱疹

8、性咽峡炎3例，溃疡性咽峡炎1例，喉炎1