肛门尖锐湿疣冷冻治疗后01%利凡诺尔与4%硼酸湿敷的临床疗效比较研究

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1、肛门尖锐湿疣冷冻治疗后0.1%利凡诺尔与4%硼酸湿敷的临床疗效比较研究万宏程1杨春俊2（通讯作者）（1安徽省六安市人民医院皮肤科237005；2安徽医科大学第一附属医院皮肤科230022）【屮图分类号】R752.3+3【文献标识码】A【文章编号】1672-5085（2012）29-0251-02【摘要】目的比较4%硼酸液和0.1%利凡诺尔液在液氮冷冻治疗肛门尖锐湿疣后湿敷对疗效和减少不良刺激的作用差别。方法口9例肛门周围尖锐湿疣患者,冷冻治疗后随机分别采用0.1%的利凡诺尔粉湿敷（E组，n=59）或4%的硼酸液湿敷（B组，n=60）。比较2组间疗效和不良反应。并对患者湿敷时刺激

2、进行白我评分分析。结果105例完成治疗随访，E组51例、B组54例；创面愈合时间B组为6〜28d,（平均10.43d）,E组为5〜26d（平均13.45d）；B组治疗次数为3.43（1〜7次）、E组为3.87（2〜8次），两组比较差异均具有显著性。关于肛门周围水肿、局部溃疡形成和大便习惯的改变以及刺激性自我评分等，2组间均存在差异。结论4%的硼酸液湿敷与0.1%利凡诺尔液湿敷相比，不仅可以提高冷冻的疗效，减少治疗次数，还可以降低不良反应的发生率，以及减少患者冷冻治疗后的不适感。【关键词】尖锐湿疣肛门利凡诺尔硼酸湿敷AComparisonstudyofcliniceffectiv

3、ebetweenethacridineandboricacidwetcompressaftertreatmentofanalgenitalwartswithcrytherapy・WanHongchengl，LiuYangshengl,YangChunjunMD2IWanhongcheng,DepartmentofDermatologyofPeople’sHospitalofLuan2Yangchunjun，DepartmentofDermatologyatthefirstAffiliatedHospitalofAnhuiMedicalUniversity.【Abst

4、ract]Tocomparetheefficacyandadverseeffectsbetween0.1%ethacridineand4%boricacidwetcompressaftertreatmentofanalgenitalwartswithcryotherapy.Methods:Onehundredandnineteenpatientswithanalgenitalwartswereenrolledintoarandomizedclinicaltrial.Theyweretreatedwithliquidnitrogencryotherapy,andthentreat

5、edwithwetcompresswith0.1%ethacridine(Egroup,n=59)or4%boricacid(Bgroup,n=60)respectively.Theefficacyandadverseeffectswererecordedandcomparedwiththetwogroups.Aquestionnaireabouttherapyexcitingwasconductedaftertreatment.Results:105patientscompletedthestudy,(Egroup,n=51)or4%boricacid(Bgroup,n=54

6、).Thewoundsurfacewashealingfrom6〜28days(10.43daysinaverage)intheBgroup,andfrom5~26days(13.45daysinaverage)intheEgroup.ThetreatmenttimesintheBgroupwas3.43(1〜7times),and3.87(2〜8times)intheEgroup.Thetreatmenttimesandwoundsurfacehealingtimebetweenthetwogroupsweresignificantdifference.Theadversee

7、ffectssuchasedemaaroundanal,localulcerationandhabitchangingaboutdefecationarousedduringwetcompressweresignificantdifferencesbetweentwogroups.Aquestionnaireaboutexcitingduringwetcompresswassign讦icantdiffereneebetweentwogroups.Conclusion:Ourexperiene