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1、·442·中国介入影像与治疗学2009年第6卷第5期ChinJIntervImagingTher,2009,Vol6,No5Imagingandclinicalmanifestationsofneuropsychopathyinsystemiclupuserythematosus3HUANGBin(DepartmentofRadiology,MunicipalHospitalofTraditionalChineseMedicineofLiuzhou,Liuzhou545001,China)[Abstract]ObjectiveToexploretheCTandMRmanifestation
2、sofneuropsychiatricsystemiclupuserythematosus(NPSLE)incorrelationwithclinicalcondition.MethodsImagingfindings,clinicaldataandlaboratoryexaminationof26NPSLEpatientswereanalyzedretrospecticely.ResultsAllpatientsexperiencedneuropsychicsymptoms:headache,sei2zure,cerebrovascularaccident,spiritabnormali
3、ty,intracranialhypertensionandmeningitis.Laboratoryexaminationofce2rebrospinalfluidof26patientswereabnormal.ThepositiverateofACLwere53184%,ofantiribosomalPwas61153%.ThepositiverateofCTfindingwas84161%(22/26),ofMRIwas92130%(24/26).CTshoweddiffuseandlocalizedlowdensityinthewhiteandgreymatter,whileMR
4、Ipresentediso2orlow2signalonT1WIandhigh2signalonT2WIincerebt2um,cerebellum,deepwhitematter,basalgangliaandbrainstem.Cerebralatrophywasdetectedin12cases,hemorrhagein4,whereasbasalgangliacalcificationwasfoundin7cases.ConclusionMRIandCTcanprovidevaluableinformationfortheearlydetectionanddifferentiati
5、onofNPSLE,andfortheevaluationofthetreatment.Forconfirmationofthediag2nosis,combinationwiththeclinicaldataisnecessary.[Keywords]Lupuserythematosus,system;Braindiseases;Tomography,X2raycomputed;Magneticresonanceimaging系统性红斑狼疮性脑病的影像学表现及临床分析3黄斌(柳州市中医院放射科,广西柳州545001)[摘要]目的探讨系统性红斑狼疮脑病(NPSLE)患者的CT、MRI表现及
6、其与临床的关系。方法收集符合NPSLE诊断标准患者26例,对其临床表现、实验室检查及CT、MR影像学表现进行回顾性分析。结果临床表现:头痛、癫痫、脑血管意外、精神异常、颅内压增高等不同程度的神经精神症状。全部患者脑脊液检查存在异常。抗心脂抗体(ACL)阳性率为53184%,抗核糖体蛋白(r2RNP)抗体阳性率为61153%。影像表现:CT扫描阳性率为84161%(22/26),MR扫描阳性率为92130%(24/26)。CT主要表现为脑内灰白质弥漫性及局灶性低密度灶;MRI主要表现为大脑、小脑、脑干及深部白质的异常信号,T1WI呈低或等信号,T2WI呈高信号。脑萎缩12例,脑出血4例,基底
7、节钙化7例。结论MR、CT的影像学表现可以对系统性红斑狼疮脑病的早期发现、鉴别诊断及疗效评价提供参考,但对系统性红斑狼疮脑病的诊断必须密切结合其他临床资料。[关键词]红斑狼疮,系统性;脑疾病;体层摄影术,X线计算机;磁共振成像[中图分类号]R593124;R81611[文献标识码]A[文章编号]167228475(2009)0520442204系统性红斑狼疮(systemiclupuserythematosus,性疾病,
