自拟方中药与西药结合治疗糖尿病肾病的临床疗效观察

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1、自拟方中药与西药结合治疗糖尿病肾病的临床疗效观察郝书华胡晖明彭彪承孙望高山李齐刘凯姚创吴金秀湖南省益阳市人民医院，湖南益阳413001［摘要］目的探讨自拟方中药与西药结合治疗糖尿病肾病(DN)的临床疗效。方法将452例糖尿病肾病患者随机分为对照组和观察组，对照组用常规西药治疗，观察组在西药常规治疗的基础上联合中药(自拟方)治疗。结果观察组和对照组总有效率分别为94.69%(214/226)和66.37%(150/226)o2组总有效率比较，差异有统计学意义(P0.05)。结论该自拟方中药结合西药治疗DN对减少尿蛋白量、改善肾功能、延缓糖尿病肾病进展、提高内生肌酹清除率有显著疗效。关键词中西医

2、结合；糖尿病肾病；肾功能衰竭［中图分类号］R4［文献标识码］A［文章编号］1674-0742(2013)01(a)・0021・02TheObservationonClinicalEffectofDiabeticNephropathyTreatedwithCombinationofWesternMedicineandSelf-madeChineseHerbalPreparationHAOShuhuaHUHuimingPENGBiaochengSUNWangGAOShanLIQiLIUKaiYAOChuangWUJinxiuYiyangPeople*sHospitalofHunanProvinc

3、en,Hunan413001zChina［Abstract］ObjectiveToobservetheclinicaleffectofDiabeticNephropathytreatedwithcombinationofwesternmedicineandself-madeChineseherbalpreparation.MethodsTorandomlydividethe452subjectswithDNintocontrolgroupandstudygroup.Thecontrolgroup自拟方中药与西药结合治疗糖尿病肾病的临床疗效观察郝书华胡晖明彭彪承孙望高山李齐刘凯姚创吴金秀湖南省

4、益阳市人民医院，湖南益阳413001［摘要］目的探讨自拟方中药与西药结合治疗糖尿病肾病(DN)的临床疗效。方法将452例糖尿病肾病患者随机分为对照组和观察组，对照组用常规西药治疗，观察组在西药常规治疗的基础上联合中药(自拟方)治疗。结果观察组和对照组总有效率分别为94.69%(214/226)和66.37%(150/226)o2组总有效率比较，差异有统计学意义(P0.05)。结论该自拟方中药结合西药治疗DN对减少尿蛋白量、改善肾功能、延缓糖尿病肾病进展、提高内生肌酹清除率有显著疗效。关键词中西医结合；糖尿病肾病；肾功能衰竭［中图分类号］R4［文献标识码］A［文章编号］1674-0742(20

5、13)01(a)・0021・02TheObservationonClinicalEffectofDiabeticNephropathyTreatedwithCombinationofWesternMedicineandSelf-madeChineseHerbalPreparationHAOShuhuaHUHuimingPENGBiaochengSUNWangGAOShanLIQiLIUKaiYAOChuangWUJinxiuYiyangPeople*sHospitalofHunanProvincen,Hunan413001zChina［Abstract］ObjectiveToobservet

6、heclinicaleffectofDiabeticNephropathytreatedwithcombinationofwesternmedicineandself-madeChineseherbalpreparation.MethodsTorandomlydividethe452subjectswithDNintocontrolgroupandstudygroup.Thecontrolgroupwastreatedwithroutinewesternmedicine,whilethestudygroupwastreatedwithcombinationofwesternmedicinea

7、ndself-madeChineseherbalpreparation.ResultsThetotaleffectiveratesofcontrolandstudygroupare94.69%(214/226)and66.37%(150/226)/respectively;andthedifferenceofeffectiveratebetweenthetwogroupsaresignificant(P0.0