阿奇霉素联合大剂量维生素C治疗小儿支原体肺炎的疗效研究.pdf

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1、2014年5月第7卷第5期下ChinJofClinig盟Q垒：：!·21·著·阿奇霉素联合大剂量维生素C治疗／bJL支原体肺炎的疗效研究蒙日安【摘要】目的分析阿奇霉素联合大剂量维生素C治疗d'JL支原体肺炎的临床效果。方法选取2012-2013年本院就诊的支原体肺炎患儿63例作为研究对象。随机分为观察组32例，行阿奇霉素联合大剂量维生素c治疗；对照组31例，行阿奇霉素治疗，比较两组疗效。结果对照组总有效率77．41％；观察组总有效率96．87％。观察组平均住院(7．1±1．6)d，夜间咳嗽消失时间(3．8±1．0)d，血清C一反应蛋白治疗前(44．27±6．85)mr／L，治疗后(4．1

2、2±O．75)ms／L；对照组平均住院(11．8±1．4)d，夜间咳嗽消失时间(7．2±1．2)d，血清C一反应蛋白治疗前(45．03±7．21)ms／L，治疗后(7．68±1．05)ms／L。两组总有效率、平均住院时间、夜间咳嗽消失时间及治疗后血清c一反应蛋白水平比较，差异均有统计学意义(P<0．05)。结论阿奇霉素联合大剂量维生素C治疗小儿支原体肺炎疗效显著，缩短疗程并缓解患儿各项不良症状。【关键词】肺炎，支原体；阿奇霉素；抗坏血酸；治疗结果【中图分类号】R725．631．3【文献标识码】A【文章编号】1674-3296(2014)05C一0021—02ClinicalEficacy

3、ofAzithromycinCombinedwithHighDosesofVitaminCTreatingPediatricMycoplasmaPneumoniaMENGRi一口，1．PharmacyDepartment．DahuaYaoAutonomousCountyMaternityandCHealthCare，Dahua530800，China【Abstract】ObjectiveToanalyzetheeficacyofazithromycincombinedwithhighdosesofvitaminCtreatingpediat-ricmyeoplasmapneumonia．

4、Methods63casesofpediatricmyeoplasmapneumoniainourhospitalfrom2012to2013asthere—searchobject．63caseswererandomlydividedintotwogroups，observationgroup(n=32)wastreatedwithazithmmycincom—binedwithhighdosesofvitaminC；Controlgroup(n=31)Wastreatedwithazithmmycin，curativeefectoftwogroupswerecompared．Resu

5、ltsT0talefectiverateofcontrolgroupWas77．41％：T0talefectiverateofobservationgroupwas96．87％．AveragehospitalizationofobservationgroupWas(7．1±1．6)d，coughdisappearedatnighttimewas(3．8±1．0)d，serumC—reactiveproteinserumbeforethetreatmentWas(44．27±6．85)ms／L，afterthetreatmentWas(4．12±0．75)mg／L；Averagehospi

6、talizationofcontrolgroupwas(11．8±1．4)d，coughdisappearedatnighttimeWas(7．2±1．2)d，serumC—reactiveproteinbeforetreatmentwas(45．03±7．21)mg／L，afterthetreatmentwas(7．68±1．05)mg／L．I'0talefec-tiverate，averagehospitalizationtime，coughdisappearedatnighttimeandaftertreatmentserumC—reactiveproteinleveloftwog

7、roupswerecompared，thediferenceswerestatisticallysignificant(P<0．05)．ConclusionClinicaleficacyofazithm-mycincombinedwithhighdosesofvitaminctreatingpediatricmycoplasmapneumoniahassignificantefect。shortenthetreat—mentcour