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时间:2020-04-20
《七氟烷与丙泊酚同等麻醉对老年患者顺式阿曲库铵肌松效应的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中华老年医学杂志2013年6月第32卷第6期ChinJGeriatr,June2013,Vo1.32,No.6659·临床研究·七氟烷与丙泊酚同等麻醉对老年患者顺式阿曲库铵肌松效应的影响邵军进吕蕾任祖华吕金英【摘要】目的比较七氟烷与丙泊酚在同等麻醉深度时对老年患者顺式阿曲库铵肌松效应的影响。方法选择7O例美国麻醉师协会(ASA)I~Ⅱ级的6O周岁以上老年患者,随机分为丙泊酚组和七氟烷组两组,每组35例。采用电刺激尺神经监测拇内收肌肌颤搐反应的方法进行肌松监测。两组分别采用丙泊酚和七氟烷进行麻醉诱导并比较两组顺式阿曲库铵在不同时间点注入速率和患者意识消失时
2、间与顺式阿曲库铵肌松起效时间。结果吸人七氟烷后检测各时问点顺式阿曲库铵的注入速率,与未吸人前(即0min)相比,分别下降了11.19、29.82%、42.28、37.15。七氟烷组的注入速率在60min之后下降较高,与丙泊酚组相比差异有统计学意义(P0.05);而顺式阿曲库铵肌松起效时间分别为(148.62±28.54)s和(96.53±23.69)s,七氟烷组起效时间短于丙泊酚组(P3、式阿曲库铵的起效时间并延长顺式阿曲库铵的延长时效。【关键词】二异丙酚;肌松弛药,中枢性;麻醉药,吸入EffectofpropofolorsevofluraneonthequalityofneuromuscularblockadewithcisatracuriumduringcomparabledepthofanesthesiainelderlypatientsSHA0Jun—Jin,LVLei,RENZu—hua,LVJin—ying.DepartmentofAnesthesia,DongyangPeopleSHospitalAffiliatedtoWe4、nzhouMedicalCollege,Dongyang3221O0,ChinaCorrespondingauthor:IVIei,Emai1:106387573@qq.corn[Abstract]ObjectiveToinvestigatetheeffectofpropofolorsevofluraneonthequalityofneuromuscularblockadewithcisatracuriumduringcomparabledepthofanesthesiainelderlypatients.MethodsAtotalof60patient5、sagedover60years[classifiedasAmericanSocietvofAnesthesiologists(ASA)physicalstatus工Ⅱ]wereselected.Patientswererandomizedinto2groups:propofo1group(inductionofanesthesiawithpropofo1)andsevofluranegroup(inductionofanesthesiawithsevoflurane)(n一35,each).Neuromuseularblockingeffectwasm6、onitoredbymUSCleresponsetoulnarnervestimulation.Theratesofcisatracuriuminjectionatdifferenttimepoints.timeoflOSSofconsciousnessandtheonsettimeofcisatracuriumneuromuscularblockwerecomparedbetweenthetwogroups.ResultsTherateofcisatracuriuminjectionwassignificantlydecreasedat60minute7、s,9Omin,120mininsevofluranegroup(29.82,42.28,37.15),andtheonsettimeofcisatracuriumneuromuscularblockwassignificantlyshorterinsevofluranegroupthaninpropofolgroup[(148.62±28.54)SWS(96.53±23.69)S,P<0.05].ConclusionsComparedwithpropofo1,sevofluranecangreatlyshortentheonsettimeofcisat8、racuriumandenhancetheeffectofcisatraeuri
3、式阿曲库铵的起效时间并延长顺式阿曲库铵的延长时效。【关键词】二异丙酚;肌松弛药,中枢性;麻醉药,吸入EffectofpropofolorsevofluraneonthequalityofneuromuscularblockadewithcisatracuriumduringcomparabledepthofanesthesiainelderlypatientsSHA0Jun—Jin,LVLei,RENZu—hua,LVJin—ying.DepartmentofAnesthesia,DongyangPeopleSHospitalAffiliatedtoWe
4、nzhouMedicalCollege,Dongyang3221O0,ChinaCorrespondingauthor:IVIei,Emai1:106387573@qq.corn[Abstract]ObjectiveToinvestigatetheeffectofpropofolorsevofluraneonthequalityofneuromuscularblockadewithcisatracuriumduringcomparabledepthofanesthesiainelderlypatients.MethodsAtotalof60patient
5、sagedover60years[classifiedasAmericanSocietvofAnesthesiologists(ASA)physicalstatus工Ⅱ]wereselected.Patientswererandomizedinto2groups:propofo1group(inductionofanesthesiawithpropofo1)andsevofluranegroup(inductionofanesthesiawithsevoflurane)(n一35,each).Neuromuseularblockingeffectwasm
6、onitoredbymUSCleresponsetoulnarnervestimulation.Theratesofcisatracuriuminjectionatdifferenttimepoints.timeoflOSSofconsciousnessandtheonsettimeofcisatracuriumneuromuscularblockwerecomparedbetweenthetwogroups.ResultsTherateofcisatracuriuminjectionwassignificantlydecreasedat60minute
7、s,9Omin,120mininsevofluranegroup(29.82,42.28,37.15),andtheonsettimeofcisatracuriumneuromuscularblockwassignificantlyshorterinsevofluranegroupthaninpropofolgroup[(148.62±28.54)SWS(96.53±23.69)S,P<0.05].ConclusionsComparedwithpropofo1,sevofluranecangreatlyshortentheonsettimeofcisat
8、racuriumandenhancetheeffectofcisatraeuri
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