经肝动脉化疗栓塞术联合经皮肝穿门静脉大剂量热碘油栓塞治疗肝转移癌.pdf

《经肝动脉化疗栓塞术联合经皮肝穿门静脉大剂量热碘油栓塞治疗肝转移癌.pdf》由会员上传分享，免费在线阅读，更多相关内容在应用文档-天天文库。

1、介入放射学杂志2014年2月第23卷第2期JInterventRadiol2014，Vo1．23，No．2—115——·肿瘤介入Tumorintervention·经肝动脉化疗栓塞术联合经皮肝穿门静脉大剂量热碘油栓塞治疗肝转移癌独建库，何伟华，邹洋，马小桔【摘要】目的探讨采用经肝动脉化疗栓塞术(TACE)联合经皮肝穿门静脉灌注大剂量加热碘油治疗肝转移癌的方法及疗效。方法肝转移癌患者124例，随机分为联合组62例和对照组62例，分别采用TACE联合经门静脉路径灌注大剂量热碘油和常规TACE治疗。结果术后复查CT、MRI，联合组瘤体缩

2、小率明显高于对照组，术后随访6、12、18、24个月，联合组总有效率为61．3％明显优于对照组的38．7％，两组差异有统计学意义(P<0．05)。结论TACE联合经皮肝穿门静脉灌注大剂量热碘油治疗肝转移癌疗效比常规TACE方法更有效，是治疗肝转移癌安全有效的选择，具有一定的临床应用价值。【关键词】肝转移癌；门静脉栓塞术；热碘油；TACE术中图分类号：R735．7文献标志码：A文章编号：1008—794X(2014)．02．0l15一O3Hepaticchemoembolizationcombinedwithpercutaneous

3、trans—hepaticpunctureofportalveinplusheatedLipiodolinfusionforthetreatmentofmetastaticlivercarcinomaDU饥一ku，HEWei—hua，ZOUYaug，MAXiao—ju．InterventionalCenter，No．150HospitalofPLA，Luoyang，HenanProvince471031，ChinaCorrespondingauthor：DU饥一ku，E-mail：jiankud@163．con【Abstract】

4、ObjectiveTodiscusstheclinicaleffectandmethodoftransarterialchemoembolization(TACE)combinedwithpereutaneoustrans—hepaticpunctureofpo~alveinplusheatedLipiodolinfusionintreatingmetastaticlivercarcinoma．MethodsAtotalof124patientswithlivermetastaticcarcinomawererandomlydiv

5、idedintocombinationgroup(n=62)andcontrolgroup(n=62)．TACEcombinedwithpercutaneoustrans—hepaticpunctureofportalveinplusheatedlargerdoseLipiodolinfusionwascarriedoutinthepatientsofthecombinationgroup，whileonlyconventionalTACEwasperformedinthepatientsofthecontrolgroup．The

6、clinicalresultswereanalyzed．ResultsPostoperativeCTandMRIexaminationsshowedthattheshrinkagerateofthetumorinthecombinationgroupwassignificantlyhigherthanthatinthecontrolgroup．Postoperativecheck-upsweremadeat6，12，18and24months．Thetotalefectiverateofthecombinationgroupwas

7、61．3％，whichwasobviouslyhigherthanthatofthecontrolgroup(38．7％)．Thedifferencebetweenthetwogroupswasstatisticallysignificant(P

8、dolinfusionismoreeffectivethanconventionalTACE．Therefore，thistechniqueshouldberecommendedinclinicalpractice．(JInterventRadio