短期针刺足三里对脂多糖诱导的大鼠急性肺损伤的预防作用

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1、短期针刺足三里对脂多糖诱导的大鼠急性肺损伤的预防作用：ArthurdeSFERREIRA,JanurioGomesMouroeLIMA,TatianaPereiraTeixeiraFERREIRA,CamilaMadeiraTavaresLOPES,RubensMEYER【摘要】目的：研究短期手法针刺足三里治疗对脂多糖诱导的实验性大鼠急性肺损伤的预防作用。方法：根据是否进行脂多糖刺激及采用的针刺方法的不同，将32只)hasalonghistoryindiseasepreventionandtreatment.

2、Casesdescription,explanations,andprescriptionsforinfectiousdiseases(traditionallycalledshanghan“catchcold”)canbefoundonbooksosttillenniaagoandarestillappliedtoclinicalpractice［4,5］.TheoryofTCMonphysiologyattributestothelungs(Fei)thebreathingprocessandthepromo

3、tionofthedefensivefunctionagainstexternalfactors,actuallyinterpretedmainlyasinfectiousagents.Suchresistanceisproperlydevelopedotionofblood(xue)［6］.Ifthedefensivefunctionispreservedand(or)theexternalagentisrelativelyised.Inthiscase,stimulationofacupointsmaybeus

4、edtoincreasethestrengthofbothlunganddefensivefunctions［6］.　　Scientificevidencerecognizedbythe［6］.　　Lipopolysaccharide(LPS)isaconstituentofcellnegativemicroorganismsthatcontributestothelocalinflammationandsystemictoxicityofinfections［13］.Invivoadministrationo

5、fbacterialLPStriggersamatoryresponses.LPSmediatesmanyofitseffectsbyligandreceptorinteractionberofimmunecells,matorymediatorsthatorchestratetheacuteinflammatoryresponse［14］.ThetherapeuticeffectsofelectroacupuncturestimulationofST36onLPSinducedALIhadbeendemon

6、strated.Effectsof30minneedleelectricstimulationatST36onehourpriortoLPSinjectionreducedlungsepsisbydoans,repeatedacupuncturetreatmentsatST36,Quchi(LI11),Xuehai(SP10),andDazhui(GV14)inducedasignificantreductioninleukocytesandlymphocytescirculatingvalues,suggest

7、ingamodulationoftheimmuneresponsesystemvianeedlestimulation［16］.Althoughelectroacupunctureiscurrentlyavailable,manualstimulationstillprisesthemostusedtechniqueonprivatepracticeindevelopingcountries.Moreover,noneofthosestudiesassessedtheprophylacticeffectsofs

8、horttermacupunctureonALI.　　TheaimofthispapermanualacupunctureonST36ontheimmunesystemresponsetoALIcausedbyLPSinstillationinaterialsandmethods　　1.1ExperimentalprotocolThirtytale,20