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时间:2017-11-13
《医药学临床医学毕业论文 脑囊虫病的mri诊断及病理分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、湖南师范大学本科毕业论文考籍号:XXXXXXXXX姓名:XXX专业:医药学临床医学论文题目:脑囊虫病的MRI诊断及病理分析指导老师:XXX二〇一一年十二月十日作者:郭会利张敏程敬亮孙骏谟【摘要】目的分析脑囊虫病的病理演变特点,探讨脑囊虫病的MRI特征及诊断价值。方法分析36例脑囊虫病的MRI表现特点,并结合12例手术后病理材料进行比较。结果脑实质型18例,脑室型4例,脑膜型3例,混合型11例,主要MRI特点:(1)囊虫存活期,病灶呈圆型,多发常见,附壁囊虫头节呈偏心型小点状影,T1WI呈略高信号,T2WI呈中低信号;囊液T1WI呈低信号,T2WI呈高信号
2、;在FLAIR上脑脊液呈低信号,而囊液呈相对高信号;周围水肿不明显。(2)囊虫退变坏死期,头节消失,囊腔扩大,周围水肿明显。(3)病灶钙化后,T1WI及T2WI均呈低信号,周围水肿消失。(4)增强扫描表现为:囊壁环状增强(24/36),或不增强(12/36);囊内小点状影增强(22/36),或不增强(14/36)。(5)脑室型:常发生于第三、四脑室,其中第三脑室1例(1/36),第四脑室3例(3/36),均引起阻塞性脑积水。(6)脑膜型:因蛛网膜粘连,而引起脑积水(2/36)。结论脑囊虫病在病理演变过程中,具有特征性的MRI表现;MRI对确定脑囊虫病的数
3、目、大小、部位等发病特点及病理演变过程具有很高的诊断价值。【关键词】脑囊虫病磁共振成像诊断价值病理分析【Abstract】ObjectiveToanalyzethepathologicalanddevelopmentalcharacteristicsofcerebralcysticercosis(CC)andexploretheMRIcharacteristicsofCCanditsdiagnosticvalue.MethodsTheMRIfindingsof36CCcaseswereanalyzedandcomparedwiththepostopera
4、tivepathologicalmaterialsof12cases.ResultsThethirty-sixcasesincluded18ofcerebral-parenchymaltype,4ofcerebral-ventriculartype,3ofmeningealtype,and11ofmixedtype.TheCCMRIfindingsarecharacterizedmainlyby:(1)frequently-encounteredmultiplecircularfociduringthecysticercussurvival:smalle
5、xcentricspottyimagesofthemuralcysticercusscolex:slightlyhighsignsonT1WIandmiddle-lowersignsonT2WI;lowersignsonT1WIandhighsignsonT2WIofthecapsularliquid;lowersignsofthecerebrospinalfluidbutrelativelyhighsignsofthecapsularliquidonFLAIR;andunremarkableperipheraledema;(2)scolexdisapp
6、earance,enlargedcapsularcavityandremarkableperipheraledemaduringcysticercusdegenerationandnecrosis;(3)lowersignsonT1WIandT2WIandperipheraledemadisappearanceafterthefocalcalcification;(4)findingsshownbytheenhancedscanning:strengthened(24/36)ornon-strengthened(12/36)cyst-wallcircul
7、arimages;strengthened(22/36)ornon-strengthened(14/36)smallintracapsularspottyimages;(5)cerebral-ventriculartypeoftenoccurringinthethirdandfourthventricles:onecaseinthethirdventricle(1/36)andthreecasesinthefourthventricle(3/36),allofwhichsufferedfromobstructivehydrocephalus;(6)hyd
8、rocephaluscausedbyarachnoidadhesion(2/36
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