冠状动脉介入治疗对非st段抬高型急性冠脉综合征并左心室功能不全患者心功能的影响

《冠状动脉介入治疗对非st段抬高型急性冠脉综合征并左心室功能不全患者心功能的影响》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、冠状动脉介入治疗对非ST段抬高型急性冠脉综合征并左心室功能不全患者心功能的影响湖南省人民医院湖南长沙410005【摘要】目的：探讨介入治疗对冠心病合并左心室功能不全心功能产生的影响。方法选取我院2012年3月-2015年3月非ST段抬高急性冠脉综合征的冠心病合并左心室功能不全患者106例，将其分为研宂组与对照组各53例。两组冠状动脉均为经冠脉造影证实含前降支近段的多支多处严重狭窄。研究组实施介入治疗及药物治疗，对照组因患考意愿未行介入治疗而仅予以药物治疗，对比两组NYHA心功能分级、左心室舒张末期内径（LVEDD）、收缩末期内径（LVE

2、SD）、左心室射血分数（LVEF）及左心室短轴缩短率（LVFS）。结果治疗前两组患者的左心室功能相关指标比较差异无统计学意义，治疗后两组患考的左心功能相关指标均有改善，研究组患者左心室舒张末内径及左心室收缩末内径两项指标的T降幅度较大，左室射血分数及左室短轴缩短率两项指标上升明显，与对照组比较,差异有统计学意义（P<0.05）。结论在药物治疗基础上，对于非ST段抬高型急性冠脉综合征合并左心室功能不全患者，对包含前降支严重病变的冠脉介入治疗可进一步改善心功能、抑制心室重塑。【关键词】急性冠脉综合征；心功能不全；介入治疗：心功能Abs

3、tract：Objective：Toinvestigatetheeffectofinterventionaltherapyontheleftventricularfunctioninpatientswithcoronaryarterydisease.Methods106patientswithnonSTsegmentelevationacutecoronarysyndromewithnon-2015segmentelevationacutecoronarysyndromeinourhospitalfromMarch2012toMarch

4、weredividedintostudygroupandcontrolgroupwith53casesineachgroup.Thetwogroupsofcoronaryarteryangiographyconfirmedthattheproximalsegmentoftheanteriordescendingbranchwasmuchmoreseverethanthatofthecoronaryartery.Thestudygroupwastreatedwithinterventionaltherapyanddrugtreatment

5、.Thecontrolgroupwastreatedwithdrugs,comparedwithtwogroupsofNYHAheartfunctionclassification,leftventricularenddiastolicdiameter(LVEDD),leftventricularejectionfraction(LVEF)，leftventricularejectionfraction(LVESD)andleftventricularshortaxisshorteningrate(LVFS)•Resultstherew

6、erenosignificantdifferencesinleftventricularfunctioninthetwogroupsbeforetreatment，andtheleftventricularfunctioninthetwogroupswereimproved.Theleftventriculardiastolicdiameterandleftventricularendsystolicdiameteroftheleftventricleweresignificantlyincreased,leftventriculare

7、jectionfractionandleftventricularshortaxisshorteningrateoftwoindicatorsincreasedsignificantlycomparedwiththecontrolgroup(P<O.O5)•Conclusiononthebasisofdrugtreatment,fornonSTelevationacutecoronarysyndromewithleftventriculardysfunction,descendingbranchofcoronaryarteryle

8、sionsonseverecontainsbeforeinterventionaltreatmentcanimprovecardiacfunctionandinhibitventricularremodel