磁共振扩散加权成像鉴别高级别胶质瘤和单发脑转移瘤的价值探讨.pdf

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1、中国血液流变学杂志.2014;24(4)571doi:10.3969/j.issn.1009-881X.2014.04.035磁共振扩散加权成像鉴别高级别胶质瘤和单发脑转移瘤的价值探讨*张宏美，邢建明，胡粟，杨玲，胡春洪（苏州大学附属第一医院影像中心，江苏苏州215006）摘要：目的探讨磁共振扩散加权成像（MRDWI）在高级别胶质瘤和单发脑转移瘤中的鉴别诊断价值。方法9例单发脑转移瘤和10例高级别胶质瘤均进行了常规磁共振成像（MRI）及扩散加权成像（DWI），在经后处理重建获得的表观扩散系数（ADC）图分别测得其肿瘤实质部分及瘤周水肿区的A

2、DC值，并进行对比分析。结果(1)9例单发脑转移瘤均表现为边界清晰的类圆形病灶，瘤周水肿带范围较广。10例高级别胶质瘤表现为不规则斑片状（n=6）或类圆形（n=4），边界清（n=4）或不清（n=6），瘤周水肿带不如转移瘤明显。(2)单发脑转移瘤和高级别胶质瘤肿瘤实质部分ADC值分别为-32-32（1.11±0.19）×10mm/s和（1.43±0.33）×10mm/s，两者比较差异无统计学意义（t=2.15，P=0.05）。单发脑转移瘤和-32-32高级别胶质瘤瘤周水肿区ADC值分别为（1.69±0.22）×10mm/s和（1.24±0.1

3、8）×10mm/s，两者比较差异有统计学意义（t=4.45，P＜0.01）。结论MRIDWI序列显示高级别胶质瘤和单发脑转移瘤瘤周水肿区的ADC值差异有统计学意义，对两者的鉴别诊断有一定帮助。关键词：磁共振成像；扩散加权；脑胶质瘤；转移瘤中图法分类号：R445.2；R739.41文献标识码：A文章编号：1009-881X(2014)04-0571-03InvestigationtheValueofMRDiffusionWeightedImaginginDifferentiatingHigh-GradeGliomasandSingleBrai

4、nMetastasesZHANGHong-mei,XINGJian-ming,HUSu,YANGLing,HUChun-hong(DepartmentofRadiology,TheFirstAffiliatedHospitalofSoochowUniversity,Suzhou,Jiangsu,215006，China)Abstract：ObjectiveTostudythevalueofMRIdiffusionweightedimagingindifferentialdiagnosisbetweenhighgradegliomasandsi

5、nglebrainmetastases.Methods9casesofsinglebrainmetastasesand10casesofhighgradegliomasunderwentconventionalMRIandDWIimaging.TheADCvalueofparenchymaandperitumoraledemaregionineachcaseweremeasuredandanalyzed.Results(1)All9casesofsinglebrainmetastasesshowedroundlesionswithawide

6、rangeofperitumoraledema.10casesofhighgradegliomasshowedirregularpatchy(n=6)orround(n=4)massandperitumoraledemazone.(2)TheADCvalueofparenchymainsinglebrain-32-32metastasesandhighgradegliomaswere(1.11±0.19)×10mm/sand(1.43±0.33)×10mm/s,respectively.Therewasnosignificantdiffere

7、ncebetweenthem(t=2.15,P=0.05).TheADCvalueofperitumoraledemaregion-32-32insinglebrainmetastasesandhighgradegliomaswere(1.69±0.22)×10mm/sand(1.24±0.18)×10mm/srespectively.Therewassignificantdifferencebetweenthem(t=4.45,P＜0.01).ConclusionMRIDWIsequencesrevealedsignificantdiffer

8、enceinADCvalueofperitumoraledemaregionbetweenhighgradegliomasandsinglebrainmetastases,whi