胆宁片结合胆肠Roux-en-Y吻合术治疗肝胆管结石临床观察.doc

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1、腥宁片结合胆肠Roux-en-Y吻合术治疗肝胆管结石临床观察【关键词】胆宁vPstyle=”TEXT-INDENT:24px”>【摘要】目的观察中药胆宁片配合胆管空肠Roux-en-Y吻合术治疗肝胆管结石的临床疗效。方法47例肝胆管结石患者术前分为两组:治疗组（胆宁片组）24例,对照组（去氢胆酸组）23例,均行胆管空肠Roux-en-Y吻合术,术后治疗组服用胆宁片,对照组服用去须胆酸，治疗时间为I年。观察两组术后病人肝功能恢复情况、症状缓解率、残石率和结石复发率。结果治疗组术后ALT、TBiL、DB的恢复和临床症状改善程度显著优于对照组（PvO.05）;随访

2、2〜3年，结石复发率治疗组低于对照组（4.35%vs35.00%,Pv0.05）;两组残石率差异无显著性（4.17%vsl3.04%,P>0.05）o结论胆宁片能有效改善术后病人的肝功能，缓解临床症状，降低术后结石复发率。关键伺肝胆管结石胆宁片胆管空肠吻合术疗效vPstyle='TEXT・INDENT:24pxnalign=center>Clinicalstudyonpatientswithhepatolithiasistreatedbydanning

3、lign=center>tabincombinationwithRoux-en-YcholangiojejunostomyLiuShikui,LiuHaiboTheRedCrossofMu-danDistrictofHe-zheCity,Shandong274000.vPstyle="TEXT-INDENT:24px">[Abstract]ObjectiveToevaluatethetherapeutic

4、effectsofDanningTabonpatientswithhepatolithiasisun'derwentRoux-en-Ycholangiojejunostomy.Methods47patientswithhepatolithiasisunderwentRoux-en-Ycholangiojejunostomyweredividedintotwogroups.DanningTabwereadministratedto24patients（DanningTabgroup）andDehydrocholintotheremaining23patient

5、s（Dehydrocholingroup）bothforoneyear.Theliverfunction,clinicalsymptoms,therateofretainedstoneandtherecurrencerateofstonewereobservedinthetwogroups.ResultsDanningTabgroupcouldimprovepatients?liverfunctionandrelieveclinicalsymptomsbetterthanehydrocholingroup（P<0.05）.Thestone'srecurren

6、cerateofDanningTabgroupwas4.35%whichwaslowerthanthatofDehy一drocholingroup（35.00%）（P<0.05）.Nosignificantdifferencewasfoundintherateofretainedstonebetweenthetwogroups.ConclusionDanningTabcouldeffectivelyimprovetheliverfunctionandrelieveclinicalsymptomsofpa一tientswithhepatolithiasis.D

7、anningTabcanalsodecreasetherecurrencerateofstonepostoperatively.KeywordshepatolithiasisdanningtabcholangiojejunostomytherapeuticeffectRoux-en-Y胆肠吻合术是治疗肝胆管结石的主要附加方式，但术后存在结石残留、结石复发、胆道感染等并发症。如何减少术后并发症并提高术后生活质量，一直是临床医生较为关注的问题。中医中西对胆

8、石症结石的防治和临床症状的改善有一定的疗效。我们应用