ahr信号通路在白癜风氧化应激发病中的作用及分子机制研究

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1、分类号R758.41616.5公开UDC密级AHR信号通路在白癜风氧化应激发病中的作用及分子机制研究王筱雯全日制培学养位类类别型学术学位临床医学一级学科(专业类)二级学科(专业)皮肤病与性病学白癜风发病机制研指培究导养方教单向师位高天文教授（主任医师）第四军医大学西京皮肤医院二O一五年十一月第四军医大学博士学位论文目录缩略语表··························································································································

2、····1中文摘要····························································································································10ABSTRACT······················································································································13前言·····················

3、···············································································································16文献回顾····························································································································171白癜风概述·····································

4、········································································172白癜风发病机制假说·····························································································173AHR信号通路···································································································

5、······254白癜风与AHR信号通路·······················································································29正文····································································································································30第一部分AHR遗传变异与白癜风关联分析及其功能学研究···············

6、···················301材料·························································································································302方法·························································································································353结果··········

7、···············································································································494讨论·························································································································56第二部分AHR通路促进线粒体生物合成对抗人黑素细胞氧化损伤的作用研究··591材料····