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1、青蒿鳖甲汤联合少量激素治疗狼疮性肾炎疗效观察［摘要］目的研究青蒿鳖甲汤联合少量激素治疗狼疮性肾炎的临床疗效。方法62例狼疮性肾炎患者均来至我院中医科及血液科门诊及住院部，按就诊顺序将其随机分为治疗组(32例)和对照组(30例)。治疗组口服青蒿鳖甲汤联合少量激素；对照组口服强的松片。结果治疗组总有效率为90.6%,对照组总有效率为66.7%,治疗组总有效率高于对照组(PV0.05)；经过观察，发现在临床症状、激素撤减情况及药物副作用方面，治疗组明显优于对照组(P<0.05)o结论运用青蒿鳖甲汤联合少
2、量激素治疗狼疮性肾炎，可明显缓解临床症状，改善实验室指标，减少激素用量，稳定病情和减少西药的副作用。［关键词］青蒿鳖甲汤；狼疮性肾炎；强的松［中图分类号］R593.242［文献标识码］A［文章编号］1673-7210(2012)08(b)-0112-02ClinicalobservationonQinghaoBiejiaDecoctioncombinedwithasmallamountofhormoneinthetreatmentoflupusnephritisWANGZhihuaDAIZhaoy
3、anQOANYaohuaTUYunZhanjiangCentralpeople'shospital,GuangdongProvince,Zhanjiang524037,China[Abstract]ObjectiveToobservetheclinicalefficacyofQinghaoBiejiaDecoctioncombinedwithasmallamountofhormoneinthetreatmentoflupusnephritis.Methods62patientswithlupusn
4、ephritiswerecomingtoourtraditionalChineseMedicineanddepartmentofhematologyinout-patientandin-pa.tientdepartment,weredividedintotwogroupsbyvisitingtheorderrandomly,thetreatmentgroupof32casesandthecontrolgroupof30cases.ThetreatmentgroupweretreatedwithQi
5、nghaoBiejiaDecoctioncombinedwithasmallamountofhormone；ThecontrolgroupweretreatedwithPrednisone・ResuItsThetotaleffectiverateofthetreatmentgroupwas90.6%,thetotaleffectiverateofthecontrolgroupwas66.7%,thetotaleffectiverateoftheteatmentgroupwashigherthant
6、hatofthecontrolgroup(P<0.05)；aftertheobservation,itwasfoundtha/tinclinicalsymptoms,hrmonereductionanddrugsideeffects,thetreatmentgroupwassignificantlybetterthanthecontrolgroup(P<0.05)・ConclusionUsingQinghaoBiejiaDecoctionwithasmallamountofhormonetotre
7、atlupusnephritis,canreduceclinicalsymptoms,improvelaboratoryparameters,reducehormonedosage,stabilizeenditionandreducethesideeffectsofWesternmedicine.[Keywords]Qinghaobiejiadecoction；Lupusnephritis；Prednisone系统性红斑狼疮(systemiclupuserythematosus,SLE)是一种多系
8、统损害，伴有多种自身抗体形成的免疫系统疾病，肾脏是常见受累器官，狼疮性肾炎(lupusnephritis,LN)是免疫复合物沉淀引起的免疫性肾炎，笔者在临床中运用青蒿鳖甲汤加减联合少量激素治疗狼疮性肾炎，取得较好临床疗效，现报道结果如下：1资料与方法1.1一般资料62例狼疮性肾炎患者均来自我院中医科及血液科门诊及住院部，按就诊顺序随机分为两组。治疗组32例，男5例，女27例，男女比例1：5.4,平均年龄(31.38±10.85)岁,平均病程(2.70±0.58)年；对照组30例，男
